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The Provenance Gap in Clinical AI: Evidence-Traceable Temporal Knowledge Graphs for Rare Disease Reasoning

A new paper introduces HEG-TKG, a system designed to address the "Provenance Gap" in clinical AI, where large language models often fabricate citations. The HEG-TKG system grounds clinical claims in temporal knowledge graphs derived from PubMed records and curated sources, ensuring 100% evidence verifiability. Evaluations showed that HEG-TKG matches baseline clinical feature coverage while providing verifiable citations, and it demonstrated significant resistance to injected clinical errors. The system is designed for on-premise deployment using open-source models to maintain patient data privacy. AI

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IMPACT Enhances trust in clinical AI by ensuring verifiable citations, potentially accelerating adoption in healthcare settings.

RANK_REASON This is a research paper detailing a novel system for improving the verifiability of AI-generated clinical information. [lever_c_demoted from research: ic=1 ai=1.0]

Read on arXiv cs.CL →

COVERAGE [1]

  1. arXiv cs.CL TIER_1 · Md Shamim Ahmed, Maja Dusanic, Moritz Nikolai Kirschner, Elisabeth Nyoungui, Jana Zsch\"untzsch, Lukas Galke Poech, Richard R\"ottger ·

    The Provenance Gap in Clinical AI: Evidence-Traceable Temporal Knowledge Graphs for Rare Disease Reasoning

    arXiv:2604.17114v2 Announce Type: replace Abstract: Frontier large language models generate clinically accurate outputs, but their citations are often fabricated. We term this the Provenance Gap. We tested five frontier LLMs across 36 clinician-validated scenarios for three rare …