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Evolutionary biologist explains why humans can't regrow limbs

Humans cannot regrow limbs because our advanced immune systems prioritize rapid wound sealing over the cellular dedifferentiation required for regeneration. While salamanders can regrow lost limbs by reverting specialized cells to an embryonic-like state to form a blastema, human cells do not undergo this process after injury. This difference is attributed to an evolutionary trade-off where a robust immune response, crucial for survival against infection and trauma, inhibits the regenerative capabilities seen in simpler organisms. AI

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Evolutionary biologist explains why humans can't regrow limbs

COVERAGE [1]

  1. Forbes — Innovation TIER_1 · Scott Travers, Contributor ·

    Why Can’t Humans Regrow Limbs? An Evolutionary Biologist Explains

    Salamanders regrow entire limbs. We share their evolutionary blueprint. So why can’t humans do the same? The answer implicates our greatest biological achievement.